The anterior interosseous nerve (AIN) is a branch of the median nerve and is principally a motor nerve. AIN palsy, also known as Kiloh-Nevin syndrome,1 is a rare syndrome characterized by complete or partial loss of motor function of the flexor pollicis longus (FPL), flexor digitorum profundus (FDP), and pronator quadratus (PQ). The symptoms include difficulty with writing and activities that require pinching motions of the index finger with the thumb. Sometimes, the middle finger also may be affected. Patients may report dull pain in the proximal forearm that gets aggravated with activity, but there is no loss of sensation.2-4
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Incidence and Related Conditions
Differential Diagnosis
Reproduced from the International statistical classification of diseases and related health problems, 10th revision, Fifth edition, 2016. Geneva, World Health Organization, 2016 https://apps.who.int/iris/handle/10665/246208
A typical patient is a middle-aged male or female working in an office. Patients initially complain about a vague pain in the proximal forearm and difficulty with writing, knitting, and other activities that require a pinching grip. Patients do not experience any abnormal tingling or prickling sensation. Patients might have suffered a viral illness before experiencing pain in the forearm. Patient's history negative for rheumatoid arthritis.
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